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Successful meeting in Vancouver. Looking forward to seeing you in Advanced Photonics 2017 in New Orleans.

It is great to attend a meeting with specific focus on certain topics as Advanced Photonics, since it is... 

Added:25 Jul 2016


The Binding Finding of a Fluorescence Lifetime

In this afternoon’s session on Luminescence and Absorption on Cellular and Tissue Levels, Prof. Victor Chernomordik gave an overview of the extensive work he and his colleagues have been undertaking to make fluorescence molecular imaging more quantitative. Much of their work has focused specifically on how to quantify human epidermal growth factor receptor 2 (HER2) concentrations (a key...

Added:27 Apr 2014



Salt and Pepper (Noise): Key Ingredients for Imaging Blood Flow

We’ve all experienced that “salt-and-pepper”, or white noise when our favorite television show cuts out on us. Well it turns out that similar “speckle” patterns are also seen when projecting laser light onto biological tissue, owing to interference patterns of the monochromatic light source. Now you might say, “so what!” and that’s probably what...

Added:25 Mar 2014


Day 1: Seeing Order in Disorder

Greetings from Washington, DC, and the OSA Controlled Light Propagation Incubator meeting! Hosted by Tom Bifano and Jerome Mertz, Boston University, USA; Sylvain Gigan, Institut Langevin, France; and Allard Mosk, University of Twente, Netherlands; today’s event brings leading researchers from the fields of biological imaging and adaptive optics together with partners from industry and...

Added:06 Mar 2014


How to fit a laser-scanning microscope into a 2mm diameter tube

Optical microscopy can provide high-resolution images of cellular morphology and matrix organization, which can be utilized to diagnose disease or trauma. However, achieving an adequate signal-to-noise ratio at imaging depths exceeding 1mm is very challenging.  As a result, the initial clinical applications for optical microscopy techniques have largely focused on skin pathology. ...

Added:28 Feb 2014


Pushing the limits of imaging resolution and penetration depth

The development of labeling techniques capable of providing customizable molecular specificity has made optical microscopy a fundamental technique in the biomedical research, and the standard compound microscope remains a fixture in just about any clinic or biomedical lab. The popularity of optical microscopy was also driven by the ability to provide resolution at the cellular level that...

Added:28 Feb 2014


It takes blood, sweat, and SERS to image single cells

Throw out those old dusty fluorescent molecules and welcome in the next generation of optical contrast agents. SERS (Surface Enhanced Raman Scattering/Spectroscopy) nanoparticles are sophisticated new contrast agents that offer some distinct advantages over conventional fluorescent molecules for investigating molecular biology.

Added:20 Feb 2014


Where would biomedicine be without optics?

Much of the emphasis in biomedical optics research has been placed on the clinical translation of our technologies -- and rightfully so!  As my fellow blogger Dr. Ken Tichauer indicates, the potential impact in the clinic is great and the future remains bright.  But as we gear up for OSA BIOMED 2014 in Miami, I will be excited to learn about some of the latest applications in basic...

Added:10 Feb 2014


Photoimmunotherapy (PIT) busts open the doors for drug delivery

Over the last decade alone, it is estimated that over $200 billion has been spent just by governments to fund cancer research [1]. Despite this enormous investment, the recently released 2014 World Heath Organization (WHO) Cancer Report suggests that cancer incidence rates and deaths from cancer are on the rise, both in more developed and less developed nations.

Added:06 Feb 2014


Beginning of a new era? Recent advances in biomedical optics light the way to long-awaited clinical translation

For decades biomedical optics has been touted as an ideal tool for diagnosing, monitoring and/or treating a vast array of health conditions owing to low-cost instrumentation, use of non-ionizing radiation, and incomparable sensitivity. All great characteristics; nonetheless, adoptions of optical devices in the clinic have been few and far-between. One could blame regulations, the high cost of...

Added:29 Jan 2014


Silk or Polyester? How Optics Can Help Determine an Answer

I love silk.  Many clothes in my wardrobe are made of 100% silk.  This is an extension of my love of all things natural. Also, it is due to the fact that I lived in Hangzhou, China which is very famous for silk.

Added:29 Jan 2013