Photonics Technologies for Connectomics Research

Hosted By: Nonlinear Optics Technical Group

31 May 2017, 20:00 - 21:00

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In this webinar hosted by the OSA Nonlinear Optics Technical Group, Dr. Yen-Yin Lin of National Tsing Hua University will introduce some of the most advanced photonics technologies that are being utilized in connectomics research, including fluorescence microscopy, nonlinear microscopy, and optogenetic manipulation. During the webinar, Dr. Lin also will discuss the specific strategy and scenario to combine these technologies to understand a comprehensive connectomic map.

Photonics technologies have greatly facilitated the progress of connectomics research in many ways. Specifically, the progress of photonics technologies results in several breakthroughs in optical microscopy technology which provides non-invasive micro-images at single neuron cell resolution. For example, with the advances of ultrafast lasers, multi-photon nonlinear microscopy has become more reliable and functional and its longer excitation wavelength enables deep-brain imaging because of the reduced scattering in turbid tissues. At the same time, fluorescence probes, optogenetics tools and tissue clearing reagent are all rapidly progressing. Now we not only can observe conventional static images, but also record dynamic changes while manipulating neuron cells.

What You Will Learn:

  • The topics cover nonlinear optical microscopy, optogenetics, and the basic goal of connectomics research.
 Who Should Attend:
  • People interested in interdisciplinary research involving ultrafast optics, nonlinear optics, imaging science, and neuroscience.


Yen-Yin Lin

Yen-Yin Lin is currently an assistant research fellow, sponsored by Ministry of Science & Technology of Taiwan, at the Brain Research Center (BRC) of National Tsing-Hua University (NTHU). He received the B.S. degree from National Taiwan University (2000) in Nuclear Science and the PhD degree from National Tsing-Hua University (2006) in Electrical Engineering. He has published 39 papers and held 13 patents on laser optics and brain imaging science. At BRC, his current research focuses on development of novel photonics systems for brain connectomics.