Big Data and Hyperspectral Imaging Uncover Hidden Regularities of Native Colours and Patterns in Cel

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Big Data and Hyperspectral Imaging Uncover Hidden Regularities of Native Colours and Patterns in Cells and Tissues

Hosted By: Laser Systems Technical Group

5 August 2020, 18:00 - 19:00
EasternTime

In this webinar hosted by the OSA Laser Systems Technical Group, Ewa Goldys, Deputy Director of the Australian Research Council Centre of Excellence for Nanoscale Biophotonics, will discuss next-generation technologies developed at the Centre for probing, imaging and interacting with the living systems. These address the key challenges of ultrasensitive detection of key analytes in real complex environments and molecular complexity, and they support both novel therapies and diagnostics.

By retooling a microscope with modern light emitting diodes and powerful software, they have been able to exploit a commonly ignored trait inherent to all cells: their individual colour expression and its patterns. The hyperspectral imaging technique pioneered by their team allows precise quantification of the native fluorescent colour of cells and tissues. Through this approach, and by using the “big data” approach and the high processing speeds of modern computers, we are now able to non-invasively image aspects of biomolecular composition of cells and tissues including those relevant to metabolism. Biomolecules such as NADH, flavins, retinoids, cytochrome C and many others can now be non-invasively monitored. As metabolic dysregulation is common across the spectrum of diseases, this next-generation methodology has impact across a broad range of biomedical scenarios, including diagnostics of various health conditions such as neurodegeneration and cancer. Prof. Goldys will provide further examples from the area of reproductive medicine and ophthalmology, as well as fundamental biological science.

What You Will Learn:

  • How to deeply probe native cell autofluorescence and obtain signatures of diagnostic value from biological image analysis


Who Should Attend:

  • Experts in novel microscopies, developers of high end and also deployable imaging technologies including from the industry
  • Clinical researchers and practitioners as well as biomedical researchers
     

About the Presenter: Ewa M. Goldys, Deputy Director, Australian Research Council Centre of Excellence in Nanoscale Biophotonics

Professor Ewa M. Goldys is Deputy Director of the Australian Research Council Centre of Excellence in Nanoscale Biophotonics (cnbp.org.au) and Professor at the Graduate School of Biomedical Engineering, the University of New South Wales, Sydney, Australia. She is Fellow of SPIE, OSA, the Australian Academy of Technological Science and Engineering (ATSE), and winner of the 2016 Australian Museum Eureka Prize for ‘Innovative Use of Technology’. She has ongoing involvement with SPIE BIOS and is part of SPIE's Photonics West where she serves as one of six track chairs. Her research spans the area of biomedical science, bioimaging, biosensing and materials science. She developed novel approaches to biochemical and medical sensing and deployable medical diagnostics. Current projects focus on non-invasive high content imaging of colours and patterns in cells and tissues.