Novel Techniques in Microscopy

Novel Techniques in Microscopy

14 - 17 April 2019
Loews Ventana Canyon Resort, Tucson, Arizona United States

Advances in optical microscopy are continually enhancing imaging performance and versatility. Examples include increasing depth penetration in scattering media, improving resolution beyond the diffraction limit, increasing speed, enhancing sensitivity and/or specificity, developing novel contrast mechanisms, addressing challenges related to intravital imaging, and more.

Speakers

  • Carlo Alonzo, Massachusetts General HospitalUnited States 
    TruResolution: An Automated Spherical Aberration Correction for Deep Multiphoton Microscopy
  • Mihaela Balu, UC Irvine Beckman Laser InstituteUnited States 
    Recent advances in multiphoton microscopy for clinical skin imaging
  • Emmanuel Bossy, Institut Laue-LangevinFrance 
    Photoacoustic imaging beyond the acoustic diffraction limit
  • Elliot Botvinick, UC Irvine Beckman Laser InstituteUnited States 
    Peri-cellular stiffness distribution in 3D type 1 collagen systems is dependent upon both cell contractility and remodeling
  • Kin Chan, BioPharmX, Inc.United States 
    Pharmacokinetic Tomography of Cutaneous Drug Delivery with Advanced Fluorescence Microscopy
  • Ji-Xin Cheng, Boston UniversityUnited States 
    Deep-Learning Stimulated Raman Scattering Microscopy
  • Nicholas Durr, Johns Hopkins UniversityUnited States 
    3D histology with deep learning fluorescence microscopy
  • Irene Georgakoudi, Tufts UniversityUnited States 
    Label-free, optical, morpho-functional cancer biomarkers
  • Ludovic Jullien, ENS, Paris 
    Out-of-Phase Imaging after Optical Modulation for Micro- and Macro-scale Multiplexed Fluorescence Imaging Against Autofluorescence and Ambient Light
  • Melike Lakadamyali, ICFO -Institut de Ciencies Fotoniques 
    Multiplexed quantitative imaging of cell´s molecular machinery with super-resolution microscopy
  • Wei Min, Columbia UniversityUnited States 
    Stimulated Raman imaging of vibrational tags: pushing new frontiers of light microscopy
  • Seemantini Nadkarni, Harvard Medical SchoolUnited States 
    Mapping the Micromechanics of the Extracellular Matrix
  • Daniel Razansky, Helmholtz Zentrum München GmbHSwitzerland 
    Rapid Volumetric Mapping of Neural Dynamics Across the Mouse Brain by Optoacoustic Calcium Imaging
  • Sylvie Roke, Ecole Polytechnique Federale de LausanneSwitzerland 
    Label-free Dynamic Lipid Membrane Potential Imaging
  • Guillermo Tearney, Wellman Center for PhotomedicineUnited States 
    Latest advances in tethered capsule endomicroscopy

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Committee

J . Quincy Brown, Tulane University, USA, Chair
Conor Evans, Massachusetts General Hospital, USA, Chair 
Kyle Quinn, University of Arkansas, USA, Program Chair 
Marie-Claire Schanne-Klein, LOB - Ecole Polytechnique, CNRS, Inserm, France, Program Chair
Virginijus Barzda, University of Toronto, Canada
Emmanuel Beaurepaire, CNRS / Ecole Polytechnique, France
Kevin Eliceiri, University of Wisconsin, USA 
Daniel Elson, Imperial College London, UK 
Alexander Jesacher, Innsbruck Medical University, Austria 
Jerome Mertz, Boston University, USA
Monika Ritsch-Marte, Innsbruck Medical University, Austria
Paco Robles, Georgia Institute of Technology, USA
Shuo Tang, University of British Columbia, Canada
Ilaria Testa, Kungliga Tekniska Hogskolan Kista, Sweden
Seok‐Hyun Yun, Massachusetts General Hospital, USA

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Plenary Session

Valentina Emiliani

Vision Institute Paris, France

Toward Circuit Optogenetics

Valentina will present how recent joint progress in light delivering approaches, opsins engineering and laser sources development have brought the field of optogenetics into a new phase that we can name ‘circuit optogenetics’, where neural circuits can be optically interrogated with milli-second temporal precision and single-cell resolution.

About the Speaker

Valentina Emiliani joined the Max Born Institute after having obtained her PhD in Physics in Rome in 1998.  She investigate carrier transport in quantum wire by near field optical microscopy (SNOM). In 2002 she moved at the European Laboratory for Nonlinear Spectroscopy to lead a research group focused on the investigation of light propagation in disordered structure by SNOM. In 2002 she moved to Paris at the Institute Jacques Monod in Paris. Her interest was to study the role of mechanical forces on the establishment of cell polarity by optical tweezers. In 2005 she was awarded with the European Young Investigator grant and formed the “Wave front engineering microscopy” group at Paris Descartes University, pioneering the use of wave front shaping for neuroscience. Valentina became research director in 2011 and Director of the Neurophotonics laboratory in 2014.

In 2018, she moved her group at the Vision Institute in Paris where she has also taken the head of the photonics department. In 2015 she obtained the Prix “Coups d’élan pour la recherche française” from the Bettencourt-Shueller foundation and in 2017 the Axa chair  “Investigation of visual circuits by optical wave front shaping “.

Aydogan Ozcan

California NanoSystems Institute UCLA, USA

Deep Learning-enabled Computational Microscopy and Sensing

Deep learning is a class of machine learning techniques that uses multi-layered artificial neural networks for automated analysis of signals or data. The name comes from the general structure of deep neural networks, which consist of several layers of artificial neurons, each performing a nonlinear operation, stacked over each other. Beyond its main stream applications such as the recognition and labeling of specific features in images, deep learning holds numerous opportunities for revolutionizing image formation, reconstruction and sensing fields. In this presentation, I will provide an overview of some of our recent work on the use of deep neural networks in advancing computational microscopy and sensing systems, also covering their biomedical applications.

About the Speaker

Aydogan Ozcan is the Chancellor’s Professor at UCLA and an HHMI Professor with the Howard Hughes Medical Institute, leading the Bio- and Nano-Photonics Laboratory at UCLA and is also the Associate Director of the California NanoSystems Institute. Ozcan holds 38 issued patents and >20 pending patent applications and is also the author of one book and the co-author of >500 peer-reviewed publications in major scientific journals and conferences.

Ozcan is the founder and a member of the Board of Directors of Lucendi Inc. and Holomic/Cellmic LLC, which was named a Technology Pioneer by The World Economic Forum in 2015. Dr. Ozcan is a Fellow of the International Photonics Society (SPIE), The Optical Society (OSA), the American Institute for Medical and Biological Engineering (AIMBE), the Institute of Electrical and Electronics Engineers (IEEE), the Royal Society of Chemistry (RSC), and the Guggenheim Foundation, and has received major awards including the Presidential Early Career Award for Scientists and Engineers, International Commission for Optics Prize, Biophotonics Technology Innovator Award, Rahmi M. Koc Science Medal, International Photonics Society Early Career Achievement Award, Army Young Investigator Award, NSF CAREER Award, NIH Director’s New Innovator Award, Navy Young Investigator Award, IEEE Photonics Society Young Investigator Award and Distinguished Lecturer Award, National Geographic Emerging Explorer Award, National Academy of Engineering The Grainger Foundation Frontiers of Engineering Award and MIT’s TR35 Award for his seminal contributions to computational imaging, sensing and diagnostics.

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Special Events

Hot Topic Discussions

Monday, 15 April, 13:00-13:45
Join your colleagues for informal discussions on a selection of current hot topics . Round tables will be set on the back patio and a different topic will be featured at each table. Topics to be discussed include, Deep Learning for Quantitative Imaging Analysis, Artificial Intelligence in Optics and Photonics and Implicit Bias . You can also bring your own topic and host a table . Please note that lunch will not be provided . We recommend that you visit the hotel’s Visita Barista or Bill’s Grill for lunch and then come on over with it.

Student & Early Career Professional Development & Networking Lunch and Learn

Monday, 15 April, 12:30–14:00
This program will provide a unique opportunity for students and early career professionals, who are close to finishing or who have recently finished their doctorate degree, to interact with experienced researchers. Key industry and academic leaders in the community will be matched for each student based on the student's preference or similarity of research interests. Students interested in all career paths – from those seeking an academic position, to those wishing to start a technology business, to those interested government/public service, to those looking to translate their benchwork skills to product development – are encouraged to apply.  Students will have an opportunity to discuss their ongoing research and career plans with their mentor, while mentors will share their professional journey and provide useful tips to those who attend. Lunch will be provided.

This Workshop is complimentary for OSA Members and space is limited. Not all who apply will be able to attend due to space limitations and priority will be given to those who have most recently or are close to graduation. 

Hosted By: OSA Foundation

Congress Reception 

Monday, 15 April, 18:30–20:00
Join your fellow attendees for the Congress Reception. Enjoy western fare while dancing the night away in the hotel's Coyote Corral. One reception ticket is included in the Full Technical Registration Fee. Guest tickets may be purchased for US $50.

 Emerging Biomedical Applications of Nonlinear Optics

Tuesday, 16 April; 12:30-14:00
Join the OSA Nonlinear Optics Technical Group for this special event exploring potential applications for nonlinear optics within the field of biomedical optics. Our speakers will give short five-minute talks on their research, which is at the intersection of nonlinear optics and biomedical engineering, followed by a moderated question and answer session. This technical group event will also provide an opportunity for you to network with others who share an interest in this area. 

Hosted By: OSA Nonlinear Optics technical Group

A Celebration of the Nobel Prize Winning Work of Arthur Ashkin

Tuesday, 16 April, 17:30–19:30
Attendees are invited to join the OSA Optical Trapping and Manipulation in Molecular and Cellular Biology Technical group as they celebrate the pioneering work of Dr. Arthur Ashkin. The event will bring together members of the optical trapping community to recognize Dr. Ashkin for receiving the 2018 Nobel Prize in Physics and to discuss his work in this area. Dr. Gabe Spalding of Illinois Wesleyan University will give a brief presentation reflecting on Ashkin’s work, which will be followed by a networking reception bringing together researchers who share an interest in optical trapping and manipulation.

Hosted By: OSA Optical Trapping and Manipulation in Molecular and Cellular Biology Technical Group

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