Skip to main content

BiOptic, Inc.


Entry By:
BiOptic Logo
BiOptic, Inc., USA

Question 1: Describe the profound impact your technology – as part of an end-user product – has had on Society. How has the population been impacted by your technology. This could be behavioral, economical, societal, etc.
Qsep100 DNA Fragment Analyzer provides quick results (less than 5 minutes) with high detection sensitivity, high resolution.

The Qsep100 provides a great economical advantage over the traditional Agarose gel Electrophoresis or Lab-on-Chip devices. You can analyze 96 samples in less than 4 hours. The disposable gel-cartridge has an integrated RFID chip which helps to track the Serial number, type of gel, expiration date and number of programmed runs with the software. One can process two 96-well sample trays at $40, which is less than $0.20 / sample run. This kind of cost savings and simplicity in operation has provided great flexibility for the end users (Biologists, Chemists…) in major research labs so they can focus more on their research work.

The Qsep100 has been used in HLA labs to speed up the HLA SSP Genotyping for the Organ Transplantation applications. The product is currently being used in the Clinical Diagnostic type applications (HPV, Factor V)

Question 2: Tell us about how your technology is unique?  What makes it stand out? How do you differentiate it from other similar technologies?
We have designed a single capillary CGE instrument with a pen-shaped compact capillary cartridge utilizing a novel micro-ball ended fiber optic-based LED-based fluorescence detection system. This automated system provides a good and easy-to-use alternative to labor intensive slab gel electrophoresis systems, also features high resolving power, excellent detection sensitivity and rapid analysis times for quantitative or qualitative analysis of dsDNA fragments.

Question 3: When first launched, did your technology make a transformational change for the end-user or incremental changes by improving a current technology?  Describe this.
We launched Qsep100 in 2012. Our technology / product provides transformational change to the Slab-gel-Electrophoresis end-users, which have been the labor intensive and time consuming type devices for the past 30 years with no major improvements.

Question 4: Give a specific example (with company names) of the buying chain for your product/technology once you sell it to the next level buyer.  Provide an example of the succession of companies your product goes through, ultimately to get to an end-user.  Example:  We produce a component that we sell to a laser systems manufacturer (name the company) who sells it to a medical OEM (name the company), who then sells it to a hospital (name the hospital).
Companies such as:
One Lambda (Thermo Fisher Scientific) use the Qsep100 for HLA SSP Genotyping applications.
BioDot (Irvine, CA) use the Qsep100 for genomic DNA (gDNA) applications prior to Real-time-PCR applications
Primex Clinical Laboratories (Van Nuys, CA) who are developing MDx type Primers for Diagnosis of HPV, Factor V, Factor II, MTHRF applications and Fragile X type PCR Markers.
Prozyme Inc. (Hayward, CA) using our CE system for Glycoprotein applications.
Distribution and OEM partners:
China OEM partner--- East Win 
Japan Distributor--- AR Brown Inc.
 Korea Distributor--- Quantum Design Korea
Taiwan Distributor---Centec Scientific, Inc and Unimed Healthcare Inc.
USA---Direct Sales

Question 5: In which vertical market(s) would you classify the end-users of this technology?

Question 6: Give us your one sentence “elevator pitch” you would use to tell a non-technical person about your technology and the critical role it plays in Society.
We have produced Qsep100, which is the most sensitive, accurate and cost-effective Analyzer in the Market that provides High-Resolution, High-Detection Sensitivity results with it’s Disposable Pen-Shaped Cartridge at less than $0.20 / sample run for bio-molecules analysis.

Question 7: Surprise Us!  What else should we know about your product/technology?
Gel-cartridge has the integrated gel-matrix with the EtBr dye sealed as part of the assembly, so there is no cause for toxicity to the environment which is the opposite for the standard Slab-gel-Electrophoresis devices. Another advantage is that it operates at 24V DC, which provides additional safety features to the end-user and has low EMI to the outside environment. And the instrument could be used in the field with DC solar