Biomedical Optics (BIOMED)

26 - 30 abril 2014
Miami Hilton Downtown, Miami, Florida, USA

Plenary Speakers

Shaping Light for Imaging, Manipulation and Transfection
Kishan Dholakia, University of St Andrews, United Kingdom

Monday, 28 April, 08:45 - 09:30
Symphony III & IV

Abstract: This talk will describe the generation and use of complex light fields for biophotonics. Applications in light sheet imaging, cell transfection and optical trapping of cells will be described.

Bio: Kishan Dholakia is Professor of Physics at the University of St Andrews. His group’s work spans fundamental photonics right through to biomedical applications. He has been fascinated with the shaping of light in amplitude, phase and polarisation. As an example, his group have pioneered the use of propagation invariant light fields in numerous areas including cell transfection, trapping and manipulation. He has published over 250 journal papers and has a h-index of 63 (Google Scholar). He is a fellow of OSA, SPIE and the Royal Society of Edinburgh

Label-free Nonlinear Endomicroscopy Imaging of Tissue Histology in vivo
Xingde Li; Johns Hopkins University, USA

Sunday, 27 April, 09:00 - 09:45
Symphony III & IV

Abstract: This talk describes the development of nonlinear endomicroscopy. The technology is capable of label-free imaging of tissue histology in vivo and in situ. Physics and engineering challenges and solutions, and potential applications will be discussed.
Bio: Dr. Xingde Li received his PhD degree in Physics from the University of Pennsylvania in 1998. He is currently a professor at the Department of Biomedical Engineering, Johns Hopkins University. His research interest focuses on development of noninvasive and translational optical micro imaging devices and technologies for early disease diagnosis and interventional guidance. He received several awards including The Teacher of the Year Award (BioE at UW), the NSF Faculty Early Career Award, the International Association of Dental Research Innovation in Oral Care Award, and the Hartwell Foundation Individual Biomedical Research Award. He serves on the editorial board of several journals in the area of biomedical optics, and he is a Fellow of OSA, SPIE, and AIMBE. His publication record can be found at google scholar.

Biomedical Imaging and Spectroscopy with Scattered Light
Lev Perelman, Harvard University, USA

Monday, 28 April, 08:00
Symphony III & IV

Abstract: Information about tissue macroscopic and microscopic structure can be obtained from the characteristics of the scattered light. We will discuss how these light scattering signatures could be used to remotely and noninvasively detect early disease in human body.

Bio: Lev T. Perelman joined the faculty of Harvard University in 2000 where he is currently a Professor with appointments in the departments of Medicine, Obgyn and Reproductive Biology and Biological and Biomedical Sciences program. He is also the Director of the Center for Advanced Biomedical Imaging and Photonics at Beth Israel Deaconess Medical Center. Prior to that he served for six years as a Principal Scientist at MIT George R. Harrison Spectroscopy Laboratory. Prof. Perelman’s current research interests are primarily focused on application of optics to medicine and biology and include light scattering spectroscopy, surface-enhanced Raman spectroscopy, nanophotonics, optical imaging, and cancer detection with light.

High Throughput, High Content Image Informatics Based on Structured-light Microscopy
Peter So, Massachusetts Institute of Technology, USA

Tuesday, 29 April, 08:00 - 08:45
Symphony III & IV

Abstract: High throughput imaging contributes to understanding how molecular level events drive cellular and tissue phenotype changes. Here, we review several novel structured light methods that significantly enhance resolution, speed, and sensitivity in microscopic imaging.

Bio: Peter So is a professor in the Department of Mechanical and Biological Engineering in the Massachusetts Institute of Technology.  Prior to joining MIT, Peter So obtained his Ph.D. from Princeton University in 1992 and subsequently worked as a postdoctoral associate in the Laboratory for Fluorescence Dynamics in the University of Illinois in Urban-Champaign.  His research focuses on developing high resolution and high information content microscopic imaging instruments.  These instruments are applied in biomedical studies such as the non-invasive optical biopsy of cancer, the mechanotransduction processes in cardiovascular diseases, and the effects of neuronal remodeling on memory plasticity.  Peter So is currently the Director of the MIT Laser Biomedical Research Center, a NIH NIBIB P41 research resource and the Program Chair of the Computational System Biology Program within the Singapore-MIT Alliance 2. 

Multispectral Multiple Scattering Low Coherence Interferometry for Tissue Diagnostics
Adam Wax, Duke University, USA

Sunday, 27 April, 09:45 - 10:30
Symphony III & IV

Abstract: We present a new method for assessing tissue health based on coherent detection of multiply scattered light.  Multispectral measurements of scattering signals image tissue components with millimeter resolution at depths of up to 1 cm.
Bio: Dr. Adam Wax joined the faculty of the Biomedical Engineering department at Duke University as an assistant professor in 2002 and was promoted to associate professor in 2008. He is currently the Theodore Kennedy Professor of Biomedical Engineer.  He is a fellow of OSA, SPIE and AIMBE. .Dr. Wax received his Ph.D. in physics from Duke in 1999 and completed his postdoctoral training at MIT. His research interests include optical spectroscopy for early cancer detection, novel microscopy and interferometry techniques. He is founder and chairman of Oncoscope, Inc., accompany founded  in 2006 to commercialize technologies developed in his laboratory.

Victor YangTaking Optical Imaging into the Operating Room: from Optical Coherence Tomography (OCT) to Optical Topographical Imaging (OTI), and Vice Versa, Victor Yang, Ryerson University and Sunnybrook Research Institute, Canada

Tuesday, 29 April, 8:45 – 9:30

Abstract: Making optical imaging available to patients in clinically relevant applications is a common challenge in biomedical optics. Identification of target application, advancement of new technology, market/commercialization interests and other factors interplay over the "life cycle" from concept, engineering design, prototyping, preclinical and clinical testing, to eventual market introduction with regulatory approval. This talk presents the intermingled paths of taking OCT and OTI into the operating room from a surgeon-engineer's perspective, and illustrates the potential clinical applications in the future.