What is Applied Industrial Optics?

By Gary Miller, US Naval Research Laboratory, USA | Posted: 5 May 2016

Applied Industrial Optics (AIO) is a unique conference where industrial professionals are asked to speak about their work, which typically is never published, unless as a patent. While many industrial societies have conferences that approach this format, the Optics and Photonics industry typically only has trade shows, such as CLEO and Photonics West. For industrial participants, these events are focused on the exhibition floor and the technical program is ancillary. AIO, this 25 - 28 July 2016 in Heidelberg, Germany as part of the Imaging and Applied Optics Congress, shifts that paradigm focusing instead on the technical program.

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Applied Industrial Optics Day 1

By Arlene Smith, Ph.D. | Posted: 9 June 2015

Dominic Murphy opening remarks

The first session of AIO 2015 - 'Flutonics Palooza' - was opened by Dominic Murphy (Pie Photonics Ltd, Ireland) with a talk titled 'Optical Wavefront Interferometry - Evolution, Challenges and Opportunities'. Dominic spoke on the challenges facing detection systems regarding information (throughput, sensitivity) and form (simplicity, size), and the advantages, such as robustness, stability and verstility, offered by Pie's optical wavefront interferometry solution.

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Salt and Pepper (Noise): Key Ingredients for Imaging Blood Flow

By Ken Tichauer | Posted: 25 March 2014

We’ve all experienced that “salt-and-pepper”, or white noise when our favorite television show cuts out on us. Well it turns out that similar “speckle” patterns are also seen when projecting laser light onto biological tissue, owing to interference patterns of the monochromatic light source. Now you might say, “so what!” and that’s probably what most would say. However, in the early 1980’s Fercher and Brier realized that movement of blood could disturb the laser speckle pattern, and this disturbance could be used to estimate blood flow [1].

In the decades following this breakthrough, Laser Speckle Imaging has been employed to visualize blood flow in the skin [2], the retina [3], and brain [4]. To date there are over 600 published articles that have included biomedical applications of Speckle Imaging. Why so popular? There are certainly many other approaches available for monitoring blood flow such as Doppler ultrasound, laser Doppler, and a slew of dynamic contrast enhanced imaging modalities. However, none of these approaches can offer the exquisite temporal resolution (milliseconds), and spatial resolution (10s of microns) that can be attained by Laser Speckle Imaging. And nowhere have these advantages been used to greater benefit than in the study of “neurovascular coupling”, which necessitates the ability to resolve the interplay between neuronal activity and blood delivery in the brain at the millisecond and micron resolution scales only offered by Speckle Imaging.

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Where would biomedicine be without optics?

By Kyle Quinn | Posted: 10 February 2014

Much of the emphasis in biomedical optics research has been placed on the clinical translation of our technologies -- and rightfully so!  As my fellow blogger Dr. Ken Tichauer indicates, the potential impact in the clinic is great and the future remains bright.  But as we gear up for OSA BIOMED 2014 in Miami, I will be excited to learn about some of the latest applications in basic science research where biomedical optics continues to play a key role. The field of optics has provided researchers advanced tools that are needed in a variety of other disciplines to optimize complex laboratory protocols, to elucidate the underlying mechanisms of disease, and to speed the preclinical development of novel therapies. Optogenetics


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Label-free imaging: What is it good for? Absolutely most things!

By Craig Goergen | Posted: 14 March 2013

Say it again! And while one of the plenary talks in the Opening General Session given by Sunny Xie (Monday, April 15th, 8:00 to 9:45am in the Ali’Ii Ballroom) titled "Label-Free Vibrational Imaging for Medicine" might be a little less funky, I am sure it will be equally as entertaining.

Dr. Xie is the Mallinckrodt Professor of Chemistry and Chemical Biology at Harvard University and is considered by many to be a founding father of the field of single-molecule enzymology. His group has also made significant contributions to the development of Coherent Anti-Stokes Raman Scattering (CARS - a dye-free method in which image structures are characterized by intrinsic vibrational contrast of their molecules). The advantage of this method is that it does not require labeling and the sample remains mostly unaffected.

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