Novel Techniques in Microscopy

Novel Techniques in Microscopy

Novel Techniques in Microscopy is focused on the development of new and creative techniques in optical microscopy for biological or biomedical applications.

Advances in optical microscopy are continually enhancing imaging performance and versatility. Examples include increasing depth penetration in scattering media, improving resolution beyond the diffraction limit, increasing speed, enhancing sensitivity and/or specificity, developing novel contrast mechanisms, addressing challenges related to intravital imaging, and more. This meeting will provide a rich collection of fresh and creative technical developments in optical microscopy for biological or biomedical applications.
 


  • Super resolution
  • Phase microscopy and tomography
  • Advances in tissue microscopy
  • Nonlinear optical imaging
Emmanuel Beaurepaire, Centre National Recherche ScientifiqueFranceMultiphoton Imaging of Developing Tissues: Multicolor and Light-sheet Approaches, Invited

Adela Ben-Yakar, University of Texas at AustinUnited StatesKagome Fiber Based Ultrafast Laser Microsurgery Probes, Invited

Stephen Boppart, Univ of Illinois at Urbana-ChampaignUnited StatesStain-free Structural and Molecular Histopathology using Programmable Supercontinuum Pulses, Invited

Shih-Chi CHEN, The Chinese University of Hong KongHong KongDMD-based Ultrafast Femtosecond Laser Beam Shaping and Its Applications in Two-photon Microscopy, Invited

Ji-Xin Cheng, Purdue UniversityUnited StatesA Hand-held Stimulated Raman Spectroscopic Imaging System, Invited

Daniel Cote, Universite LavalCanadaMolecular order with polarimetric measurements during neurodegeneration , Invited

Marcos Dantus, Michigan State UniversityUnited StatesMultimodal Biomedical Imaging with Programmable Pulses from a Yb Fiber Laser, Invited

Joseph Izatt, Duke UniversityUnited StatesNovel Multi-Modal Sub-Diffraction Imaging Modalities Enabled by Structured Illumination Microscopy, Invited

Alexander Jesacher, Innsbruck Medical UniversityAustriaImage Scanning Microscopy with Engineered Point Spread Functions, Invited

Dong Li, Institute of Biophysics, CASUnited StatesAdvances in Structured Illumination Microscopy for Super-resolution Live Cell Imaging, Invited

Jerome Mertz, Boston UniversityUnited StatesHigh Dynamic Range Imaging in Brain Tissue, Invited

Eric Potma, University of California IrvineUnited StatesAdvances in Vibrationally Resonant Sum-frequency Generation Microscopy, Invited

Marie-Claire Schanne-Klein, LOB - Ecole Polytechnique, CNRS, InsermFranceSecond Harmonic Imaging of Collagen Organization in Connective Tissues: Quantitative Approaches and Applications to Biomechanics, Invited

Gary Tearney, Wellman Center for PhotomedicineUnited StatesTethered Capsule Endomicroscopy: A new window into the gastrointestinal tract , Invited

Joshua Vaughan, University of WashingtonUnited StatesSuper-resolution Microscopy Made Simple, Invited

Chair

Paul CampagnolaUniversity of Wisconsin-Madison, United States
Conor EvansMassachusetts General Hospital, United States

Member

Chen DongNational Taiwan University, Taiwan
Irene GeorgakoudiTufts University, United States
Tarl ProwSchool Medicine, The Univ Queensland
Jianan QuHong Kong Univ of Science & Technology, Hong Kong
Kyle QuinnUniversity of Arkansas, United States
Monika Ritsch-MarteInnsbruck Medical University, Austria
Francisco RoblesGeorgia Institute of Technology, United States
Shuo TangUniversity of British Columbia, Canada
Jie XiaoJohns Hopkins University, United States
Zahid YaqoobMassachusetts Institute of Technology, United States
Seok-Hyun YunHarvard Medical School, United States

Student & Early Career Professional Development & Networking Program

Monday, 3 April, 12:00–13:30
Catalina Ballroom, Upper Level/Fourth Floor


Join us for an interactive lunch and learn program focused on professional development within the Bio Photonics field. This program will engage students and early career professionals with the key leaders in the field who will share their professional development journey and provide useful tips to those who attend. The program is complimentary for OSA Members and lunch will be provided.

Sponsored by 


Welcome Reception with Exhibitors

Monday, 3 April, 18:00–19:30
Fairbanks Ballroom, Lobby Level


Join your fellow attendees for the Congress Reception. Enjoy delectable fare while networking. The reception is open to committee/presenting author/student and full conference attendees. Conference attendees may purchase extra tickets for their guest.

Grant Writing Workshop for Young Investigators

Tuesday, 4 April, 07:00 – 08:30
Catalina Ballroom, Upper Level/Fourth Floor

Join the leaders of the OSA Tissue Imaging and Spectroscopy Technical Group, Paul Campagnola and Kyle Quinn, for a workshop aimed at helping young investigators develop competitive grant proposals. The workshop will cover how to properly construct a specific aims page for National Science Foundation and National Institute of Health grants, with both good and bad examples being provided. Participants are encouraged to bring their own grant proposals to the workshop as assistance in reviewing and improving the proposals will be offered. An RSVP is required for this technical group event as breakfast will be provided. Contact TGactivities@osa.org to register, pending availability.

Sponsored by

Strategies for Commercialization and Dissemination of Non-Clinical Optical Technologies

Tuesday, 4 April, 12:15–14:00
Catalina Ballroom, Upper Level/Fourth Floor


This panel discussion and networking luncheon will discuss and debate the best ways to get your latest invention into the hands of other researchers and end-users. Although the path for medical technologies involves complex clinical trials and FDA approval, technologies for research applications such as microscopes and fluorescent proteins can be much more rapidly translated and can provide rapid, high impact for scientific research. There are many approaches: in-lab support, open-source dissemination, start-ups, or licensing, each with their own pros and cons. After an introduction to the topic we will hear viewpoints and experiences from a range of successful translators and industry experts followed by a panel discussion. There will then be an opportunity for small group discussions and networking. Students and post-docs welcome! A free lunch will be provided to the first group of attendees.


Joint Poster Session

Tuesday, 4 April, 15:30 - 17:00
Fairbanks Ballroom


Posters are an integral part of the technical program and offer a unique networking opportunity, where presenters can discuss their results one-to-one with interested parties. Each author is provided with a board on which to display the summary and results of his or her paper.

OSA Optical Trapping and Manipulation in Molecular and Cellular Biology Technical Group Networking Event

Tuesday, 4 April 2017, 18:00–19:00
Catalina Ballroom, Upper Level/Fourth Floor


Join members of the Optical Trapping and Manipulation in Molecular and Cellular Biology Technical Group for a chance to learn more about this group while connecting with your peers and colleagues in the community over refreshments. Steven Neale and Peter Reece, who lead this OSA Technical Group, will be hosting this networking event for members on Tuesday evening. An RSVP is requested for this technical group event; please contact TGactivities@osa.org to register.

Sponsored by 



Bridging Medicine and Biomedical Technology: Enhancing Translation of Fundamental Research to Patient Care Special Session

Wednesday, 5 April, 08:30–10:00
Bel Aire Ballroom Ballroom, Lobby Level


This special all-congress session will briefly introduce the fundamentals of translational research and highlight, through two examples of important clinical problems, the challenges to overcome by physician scientists in order to identify, develop and bring to clinical practice novel biomedical technologies that provide relevant solutions.
One example in dermatology features the development of novel diagnostics for cellulitis. Cellulitis is a common and costly bacterial infection of the skin. Currently there are no objective diagnostics and therefore diagnosis depends on clinical exam alone. However, due to the many clinical mimics of cellulitis, misdiagnosis of cellulitis occurs in over one-third of patients. The misdiagnosis of cellulitis leads to unnecessary hospitalization, overuse of antibiotics, and over half a billion dollars in spending per year. Strategic approaches to develop novel diagnostics include non-invasive optical techniques and minimally invasive skin sampling, however significant technical challenges remain.

The other example in ophthalmology presents a new surgical procedure to prevent the development of high myopia. Briefly, the mechanism behind high myopia is an over-elongation of the eye during its growth period. This elongation can be halted by modulating the biomechanical properties of the growing sclera - in particular, by inducing crosslinks in the extracellular matrix. Several approaches have been made to induce those scleral crosslinks, all with certain difficulties.

The panel discussion that will conclude the session will give an opportunity for audience to ask questions and engage the dialogue with other participants and the speakers. 

Steven Chu
Stanford University, USA

Steven ChuNew Probes and Approaches to Optical, Electron Microscopy and Future Applications

We will discuss our development of rare earth and diamond nanoparticle probes to visualize the molecular organization of multiple proteins in cells and tissue. With SEM/cathodoluminescence imaging, we want to identify interacting proteins with cellular ultrastructure such as cellular membranes, organelles, synapses and vesicles.

Bio: Steven Chu is the William R. Kenan, Jr., Professor of Physics and Professor of Molecular & Cellular Physiology in the Medical School at Stanford University. His has published over 275 papers in atomic and polymer physics, biophysics, biology, batteries, and holds 11 patents. Currently, he is developing new optical nanoparticle probes for applications in biology and biomedicine, exploring new approaches to lithium ion batteries, PM2.5 air filtration and other applications of nanotechnology.

 
Dr. Chu was the 12th U.S. Secretary of Energy from January 2009 until the end of April 2013. As the first scientist to hold a Cabinet position and the longest serving Energy Secretary, he recruited outstanding scientists and engineers into the Department of Energy. He began several initiatives including ARPA-E (Advanced Research Projects Agency – Energy), the Energy Innovation Hubs, the U.S. – China Clean Energy Research Centers (CERC), and was personally tasked by President Obama to assist BP in stopping the Deepwater Horizon oil leak.

Prior to his cabinet post, he was director of the Lawrence Berkeley National Laboratory and Professor of Physics and Molecular and Cell Biology at UC Berkeley. Previously he was the Theodore and Francis Geballe Professor of Physics and Applied Physics at Stanford University. He helped launch Bio-X at Stanford University, a multi-disciplinary institute combining the physical and biological sciences with medicine and engineering, and the Kavli Institute for Particle Astrophysics and Cosmology. Previously he was head of the Quantum Electronics Research Department at AT&T Bell Laboratories.

Dr. Chu has dozens of awards including the 1997 Nobel Prize in Physics contributions to laser cooling and atom trapping. He has 29 honorary degrees and is a member of the National Academy of Sciences, the American Philosophical Society, the American Academy of Arts and Sciences, the Academia Sinica, and is a foreign member of the Royal Society, the Royal Academy of Engineering, the Chinese Academy of Sciences, and the Korean Academy of Sciences and Technology.


Subra Suresh
Carnegie Mellon University, USA

Subra SureshCell Biophysics and Human Diseases


This presentation will examine how properties of biological cells influence human diseases, and vice versa, from the perspectives of biophysics and bioengineering.  Experimental and computational results will be presented along with specific examples in the context of infectious diseases, hereditary blood disorders, and human cancers.

Bio: Subra Suresh is the President of Carnegie Mellon University where he holds faculty appoints in the College of Engineering, Heinz College of Public Policy and Management, and the School of Computer Science.  A former Director of the National Science Foundation and recipient of 11 honorary doctorate degrees, Suresh is an elected member of the U.S. National Academies of Sciences, Engineering and Medicine along with the American Academy of Arts and Sciences and the National Academy of Inventors.  Suresh is the author/coauthor of over 250 journal articles and co-inventor in 25 patent applications involving research at the intersections of engineering, science and medicine, particularly into the mechanical behavior of engineered materials and the effects of cell properties on human diseases.


Laura Waller
University of California Berkeley, USA

Laura WallerComputational Microscopy for High-Throughput Science


Computational microscopy involves joint design of imaging system hardware and software, optimizing across the entire pipeline from acquisition to reconstruction. This talk will describe methods for fast acquisition and Gigapixel-scale image reconstruction with simple and inexpensive optics.



Bio: Laura Waller is the Ted Van Duzer Endowed Associate Professor of Electrical Engineering and Computer Sciences (EECS) at UC Berkeley, a Senior Fellow at the Berkeley Institute of Data Science, and affiliate in Bioengineering and Applied Sciences & Technology. She was a Postdoctoral Researcher and Lecturer of Physics at Princeton University from 2010-2012 and received B.S., M.Eng. and Ph.D. degrees in EECS from the Massachusetts Institute of Technology (MIT) in 2004, 2005 and 2010, respectively. She is recipient of the Moore Foundation Data-Driven Investigator Award, Bakar Fellowship, Carol D. Soc Distinguished Graduate Mentoring Award, Agilent Early Career Profeessor Award Finalist, NSF CAREER Award and Packard Fellowship for Science and Engineering.