Optical Trapping Applications (OTA)

Optical Trapping Applications (OTA)

Optical Trapping Applications encompasses all areas of particle manipulation and measurement, from optical manipulation to acoustic trapping, emphasizing new and developing application areas.

This meeting covers the whole range of topical particle manipulation technologies currently being developed for studies in biophysics, single molecule, single cell and tissue level analysis, lab-on-a-chip development, optomechanical cooling, environmental monitoring and theoretical underpinnings. Technologies to be considered include optical tweezers and associated techniques, but will try and capture synergies between different trapping and manipulation modalities such as acoustic trapping and electrical trapping with a view to encouraging discussion between different user groups and the development of new hybrid techniques.


  1. 1. Optical Manipulation Fundamentals and Technologies
    • Holographic optical tweezers and beam shaping, adaptive optics techniques
    • Particle dynamics
    • Opto-mechanical cooling
    • Cell stretching
    • Mircorheology
    • High force optical tweezers
    • Photophoresis
    • Optical trap modelling and theoretical underpinnings
    • Nanoparticle manipulation
    • Plasmonic manipulation
    • Integrated and near-field optical trapping
  2. 2. Optical Manipulation Applications
    • Single molecule biophysics
    • Cellular mechanics and mechanotransduction
    • Cellular adhesion
    • Non-equilibrium statistical mechanics
    • Nanoscale & quantum sensing
    • Environmental sensing and aerosol analysis
    • Laser cellular surgery and photoporation
    • Optofluidics/microfluidics
    • Integration with spectroscopic techniques
  3. 3. Alternative Particle Manipulation Techniques
    • Magnetic tweezers
    • Electrical manipulation: Electrodynamic balance, dielectrophoresis etc
    • Acoustic manipulation and trapping
    • Microfluidic manipulation
    • Optoelectronic Tweezers
    • AFM applied to techniques studied by optical manipulation
Eric Betzig, Janelia Research Campus, Howard Hughes Medical Institute, USAImaging Life at High Spatiotemporal Resolution, Plenary
Nobel Prize Winner in Chemistry 2014

Tayyaba Hasan, Harvard Medical School, Massachusetts General Hospital, USAPhotodynamic Therapy (PDT): A Photochemical Slice of Clinical Biophotonics, Plenary

W.E. Moerner, Stanford Univ., USAPupil Plane Modulation to Extract Information from Single-Molecule Emitters for Super-Resolution Microscopy, Plenary
Nobel Prize Winner in Chemistry 2014

Gabriella Cipparrone, Universita della CalabriaItalyChiral Optomechanics of Soft Matter Based Microparticles, Invited

Elisabet Codina, ImpetuxSpainForce Measurements in Complex Samples with Optical Tweezers, Invited

David Collins, Singapore Uni of Tech. and DesignSingapore2D Individual Particle Grids Patterned with Surface Acoustic Waves, Invited

Cornelia Denz, Westfaelische Wilhelms Univ MunsterGermanyComplex Light for Optical Micro-Manipulation: Amplitude, Phase And Polarization Modulation, Invited

Alper Kiraz, Koç UniversityTurkeyDye Lasing and Laminar Flow-Induced Dissolution in Hydrodynamically Trapped Oil Microdroplets, Invited

Keir Neuman, National Institutes of HealthUnited StatesUntwisting and Unzipping: Magnetic Tweezers Based Measurements of DNA Processing Enzymes, Invited

Timo Nieminen, School of Mathematics and PhysicsAustraliaTheory and Practice of Computational Modeling and Simulation of Optical Tweezers, Invited

Giuseppe Pesce, Univ degli Studi di Napoli Federico IIItalyCharacterization of Surface Properties of Bacterial Spores Using Optical Tweezers, Invited

David Phillips, University of GlasgowUnited KingdomHydrodynamic Interactions in Driven Systems, Invited

Arnd Pralle, State University College at Buffalo SUNYThermal Noise Imaging of Cell Membrane Stiffness and Tracking of Membrane Protein Motion, Invited

Stephen Simpson, Institute of Scientific Instruments ASCRCzech RepublicShape Adapted Optical Forces And Interactions, Invited

Giorgio Volpe, University College LondonUnited KingdomOptical Manipulation with Random Light Fields: From Fundamental Physics to Applications, Invited

Michael Woodside, University of AlbertaCanadaStructure Formation in Single Biological Molecules as a Diffusive Process Probed by Optical Tweezers, Invited
 

General Chairs
Steven Neale, Univ. of Glasgow, UK
Peter Reece, Univ. of New South Wales, Australia
 
Program Chairs
Reuven Gordon, Univ. of Victoria, Canada
Lene Oddershede, The Niels Bohr Institute, Denmark
 
Program Committee
Tomas Cizmar, Univ. of Dundee, UK
Andrew Forbes, CSIR National Laser Centre, South Africa
Nancy Forde, Simon Fraser Univ., Canada
Simon Hanna, Univ. of Bristol, UK
Brooke Hester, Appalachian State Univ., USA
Tony Jun Huang, Pennsylvania State Univ., USA
Carlos Lopez-Mariscal, US Naval Research Laboratory, USA
Onofrio Marago, CNR-IPCF, Italy
David McGloin, Univ. of Dundee, UK
Jack Ng, Hong Kong Baptist Univ., Hong Kong
Peter Pauzauskie, Univ. of Washington, USA
Ruben Ramos-Garcia, Inst. Nat Astrofisica Optica Electronica, Mexico
Giulia Rusciano, Univ. degli Studi di Napoli Federico II, Italy
Giovanni Volpe, Bilkent Univ., Turkey
Pavel Zemanek, Institute of Scientific Instruments ASCR, Czech Republic
.

Conference Plenary Session

Monday, 13 April, 08:00 – 10:00

Eric Betzig, Janelia Research Campus, Howard Hughes Medical Institute, USA
Tayyaba Hasan, Harvard Medical School, Massachusetts General Hospital, USA
W.E. Moerner, Stanford Univ., USA

Conference Reception

Monday, 13 April, 18:30 – 20:00
Join your fellow attendees for the Congress Reception. Enjoy delectable fare while networking. The reception is open to committee/presenting author/student and full conference attendees. Conference attendees may purchase extra tickets for their guest.

Industry Program
Tuesday, 14 April 10:30 - 13:30

Making the Connection between Biomedical Industry Products and Current Research in Optics and Photonics
Keynote Session

Eric Buckland, CEO, Bioptigen, USA

Panel Session

Panelists from the academic, industrial, financial and agency funding world will discuss the challenges that exist when taking scientific knowledge from the bench-top to the patient-side. From success stories, and some misadventures, we will learn from the panelist the best practices to commercializing the research presented at the conference. Funding issues in the start-up phase may be discussed; regulatory hurdles along the way examined; recovery from missteps reviewed; even challenges once a company matures and is ripe for its leaders to begin the exit process may be pondered. Bring questions and expect a highly interactive session with those who have ventured down this road.

Moderator:
Brian Wilson, Senior Scientist, University Health Network, Canada

Participating panelists:
Eric Buckland, CEO, Bioptigen, USA
Lindsay Machan, Associate Professor, Dept. of Radiology, Univ. of British Columbia, Canada
Brian Pogue, Professor, Engineering Science, Dartmouth College, USA; President, DoseOptics, LLC, USA
Edmund Talley, Program Director, National Inst. of Neurological Disorders and Stroke, USA
Adam Wax, Theodore Kennedy Professor, Duke University, USA; Founder and Chairman of Oncoscope, Inc., USA

Bright Ideas Pitch Panel Luncheon

Sponsored by: Hamamatsu

Invitation to Present Your New Technology and Innovative Ideas to Entrepreneurs & Venture Capitalists

Do you have a startup or an idea for a new company? Present your technology, explain why it’s valuable and discuss the next steps to commercialization.

This is a unique opportunity to present and collaborate with entrepreneurs and venture capital panelists about your emerging company and/or new technologies that may offer solutions to the challenges faced by professionals in the life sciences.

Share your dream and receive valuable direction from those that have experienced the excitement and trepidation of starting a photonics business.

Get both immediate market and investor feedback during the “OSA Bright Ideas Luncheon” by presenting your idea to the Entrepreneur and VC Panel.

Our panel of experts will give you their advice on what you need to do to launch a new company or take your startup to the next level.

In return for your brief presentation you will get the benefit of our panel’s decades of experience in commercializing photonics. 5-minute presentations will be followed by comments and suggestions from our panel of experts.

Industry Program Committee

Alain Villeneuve, President, Optav Solutions Inc., Canada
Alex Fong, Senior VP, Life Sciences and Instrumentation, Gooch and Housego, USA
Tom Haslett, CTO, Avo Photonics, USA
Ken Kaufmann, Marketing Director, Hamamatsu Corp., USA

Joint Poster Session

Tuesday, 14 April, 15:30 – 16:30
Posters are an integral part of the technical program and offer a unique networking opportunity, where presenters can discuss their results one-to-one with interested parties. Each author is provided with a board on which to display the summary and results of his or her paper.

Eric Betzig

Janelia Research Campus, Howard Hughes Medical Institute, USA

Nobel Prize Winner in Chemistry 2014

Imaging Life at High Spatiotemporal Resolution
I will describe three different technologies that balance the inevitable tradeoffs of spatial resolution, speed, and non-invasiveness in fluorescence microscopy: 3D localization microscopy of cellular ultrastructure; nonlinear structured illumination microscopy of live cell dynamics in the sub-100 nm regime; and lattice light sheet microscopy of rapid 3D dynamic processes in vivo.


Tayyaba Hasan

Harvard Medical School, Massachusetts General Hospital, USA

Photodynamic Therapy (PDT): A Photochemical Slice of Clinical Biophotonics
This presentation will focus on the challenges associated with applying PDT as a theranostic modality for complex disease. Intricacies associated with formulation and drug delivery, dosimetry, and combination therapies that address cancer-sustaining pathways will be discussed.


W.E. Moerner

Stanford University, USA

Nobel Prize Winner in Chemistry 2014

Pupil Plane Modulation to Extract Information from Single-Molecule Emitters for Super-Resolution Microscopy
Single-molecule imaging and active control of concentration lead to super-resolution microscopy for various applications.   Pupil plane phase modulation is a powerful tool to maximize information about 3D position, orientation, and other properties of the nanoscale emitters.