Novel Techniques in Microscopy (NTM)

Novel Techniques in Microscopy (NTM)

Novel Techniques in Microscopy is focused on the development of new and creative techniques in optical microscopy for biological or biomedical applications.

Advances in optical microscopy are continually enhancing imaging performance and versatility. Examples include increasing depth penetration in scattering media, improving resolution beyond the diffraction limit, increasing speed, enhancing sensitivity and/or specificity, developing novel contrast mechanisms, addressing challenges related to intravital imaging, and more. This meeting will provide a rich collection of fresh and creative technical developments in optical microscopy for biological or biomedical applications.


  1. Super resolution
  2. Phase microscopy and tomography
  3. Advances in tissue microscopy
  4. Nonlinear optical imaging
Eric Betzig, Janelia Research Campus, Howard Hughes Medical Institute, USAImaging Life at High Spatiotemporal Resolution, Plenary
Nobel Prize Winner in Chemistry 2014

Tayyaba Hasan, Harvard Medical School, Massachusetts General Hospital, USAPhotodynamic Therapy (PDT): A Photochemical Slice of Clinical Biophotonics, Plenary

W.E. Moerner, Stanford Univ., USAPupil Plane Modulation to Extract Information from Single-Molecule Emitters for Super-Resolution Microscopy, Plenary
Nobel Prize Winner in Chemistry 2014

Randy Bartels, Colorado State UniversityUnited StatesSingle Pixel Tomographic Fluorescent Imaging with Spatial-temporal Modulated Illumination Light, Invited

Virginijus Barzda, University of TorontoCanadaNonlinear Stokes Mueller Polarimetric Microscopy, Invited

Michelle Digman, University of California, IrvineUnited States3D Nanoimaging and Detection of Molecular Flow using the nSPIRO Method, Invited

Conor Evans, Massachusetts General HospitalUnited StatesCARS Microscopy for Visualizing Treatment Response in Skin, Invited

Steven Jacques, Oregon Health and Science UniversityUnited StatesProbing Nanoscale Tissue Structure using Light Scattering, Invited

Jonathan Liu, University of WashingtonUnited StatesRecent Innovations in Dual-Axis Confocal (DAC) Microscopy for Clinical Applications, Invited

Julian Moger, University of ExeterUnited KingdomImaging Living Plant Tissues with Coherent Raman Scattering (CRS) Microscopy, Invited

Melissa Skala, Vanderbilt UniversityUnited StatesNonlinear Microscopy and Population Density Modeling of Tumor Cell Metabolism, Invited

Alexander Small, California State Polytechnic UniversityUnited StatesPotential Information Gains from Superresolution with Correlated Emitters, Invited

Benjamin Vakoc, Harvard Medical SchoolUnited StatesQuantitative Blood Flow Imaging Over Wide Fields Using Optical Coherence Tomography, Invited

Laura Waller, University of California BerkeleyUnited StatesPhase Microscopy and 3D Imaging with Partially Coherent Light, Invited

Chris Xu, Cornell UniversityUnited StatesIn Vivo Multiphoton Imaging of Mouse Brain, Invited
General Chairs
Paul Campagnola, Univ. of Wisconsin-Madison, USA
Eric Potma, Univ. of California Irvine, USA
 
Program Committee
Joerg Enderlein, Georg-August-Univ. Gottingen, Germany
Conor Evans, Massachusetts General Hospital, USA
Xingde Li, Johns Hopkins Univ., USA
Varun Raghunathan, Agilent Technologies, USA
Albert Stolow, Univ. of Ottawa, Canada
Shuo Tang, Univ. of British Columbia, Canada
Peter Török, Imperial College London, UK
Volker Westphal, Max-Planck-Inst Biophysikalische Chemie, Germany
Seok-Hyun Yun, Harvard Medical School, USA

Conference Plenary Session

Monday, 13 April, 08:00 – 10:00

Eric Betzig, Janelia Research Campus, Howard Hughes Medical Institute, USA
Tayyaba Hasan, Harvard Medical School, Massachusetts General Hospital, USA
W.E. Moerner, Stanford Univ., USA

Conference Reception

Monday, 13 April, 18:30 – 20:00
Join your fellow attendees for the Congress Reception. Enjoy delectable fare while networking. The reception is open to committee/presenting author/student and full conference attendees. Conference attendees may purchase extra tickets for their guest.

Industry Program
Tuesday, 14 April 10:30 - 13:30

Making the Connection between Biomedical Industry Products and Current Research in Optics and Photonics
Keynote Session

Eric Buckland, CEO, Bioptigen, USA

Panel Session

Panelists from the academic, industrial, financial and agency funding world will discuss the challenges that exist when taking scientific knowledge from the bench-top to the patient-side. From success stories, and some misadventures, we will learn from the panelist the best practices to commercializing the research presented at the conference. Funding issues in the start-up phase may be discussed; regulatory hurdles along the way examined; recovery from missteps reviewed; even challenges once a company matures and is ripe for its leaders to begin the exit process may be pondered. Bring questions and expect a highly interactive session with those who have ventured down this road.

Moderator:
Brian Wilson, Senior Scientist, University Health Network, Canada

Participating panelists:
Eric Buckland, CEO, Bioptigen, USA
Lindsay Machan, Associate Professor, Dept. of Radiology, Univ. of British Columbia, Canada
Brian Pogue, Professor, Engineering Science, Dartmouth College, USA; President, DoseOptics, LLC, USA
Edmund Talley, Program Director, National Inst. of Neurological Disorders and Stroke, USA
Adam Wax, Theodore Kennedy Professor, Duke University, USA; Founder and Chairman of Oncoscope, Inc., USA

Bright Ideas Pitch Panel Luncheon

Sponsored by: Hamamatsu

Invitation to Present Your New Technology and Innovative Ideas to Entrepreneurs & Venture Capitalists

Do you have a startup or an idea for a new company? Present your technology, explain why it’s valuable and discuss the next steps to commercialization.

This is a unique opportunity to present and collaborate with entrepreneurs and venture capital panelists about your emerging company and/or new technologies that may offer solutions to the challenges faced by professionals in the life sciences.

Share your dream and receive valuable direction from those that have experienced the excitement and trepidation of starting a photonics business.

Get both immediate market and investor feedback during the “OSA Bright Ideas Luncheon” by presenting your idea to the Entrepreneur and VC Panel.

Our panel of experts will give you their advice on what you need to do to launch a new company or take your startup to the next level.

In return for your brief presentation you will get the benefit of our panel’s decades of experience in commercializing photonics. 5-minute presentations will be followed by comments and suggestions from our panel of experts.

Industry Program Committee

Alain Villeneuve, President, Optav Solutions Inc., Canada
Alex Fong, Senior VP, Life Sciences and Instrumentation, Gooch and Housego, USA
Tom Haslett, CTO, Avo Photonics, USA
Ken Kaufmann, Marketing Director, Hamamatsu Corp., USA

Joint Poster Session

Tuesday, 14 April, 15:30 – 16:30
Posters are an integral part of the technical program and offer a unique networking opportunity, where presenters can discuss their results one-to-one with interested parties. Each author is provided with a board on which to display the summary and results of his or her paper.

Eric Betzig

Janelia Research Campus, Howard Hughes Medical Institute, USA

Nobel Prize Winner in Chemistry 2014

Imaging Life at High Spatiotemporal Resolution
I will describe three different technologies that balance the inevitable tradeoffs of spatial resolution, speed, and non-invasiveness in fluorescence microscopy: 3D localization microscopy of cellular ultrastructure; nonlinear structured illumination microscopy of live cell dynamics in the sub-100 nm regime; and lattice light sheet microscopy of rapid 3D dynamic processes in vivo.


Tayyaba Hasan

Harvard Medical School, Massachusetts General Hospital, USA

Photodynamic Therapy (PDT): A Photochemical Slice of Clinical Biophotonics
This presentation will focus on the challenges associated with applying PDT as a theranostic modality for complex disease. Intricacies associated with formulation and drug delivery, dosimetry, and combination therapies that address cancer-sustaining pathways will be discussed.


W.E. Moerner

Stanford University, USA

Nobel Prize Winner in Chemistry 2014

Pupil Plane Modulation to Extract Information from Single-Molecule Emitters for Super-Resolution Microscopy
Single-molecule imaging and active control of concentration lead to super-resolution microscopy for various applications.   Pupil plane phase modulation is a powerful tool to maximize information about 3D position, orientation, and other properties of the nanoscale emitters.